Celigo in der Virologie
Die präzise whole-well Abbildung des Celigo macht das System besonders geeignet für Anwendungen in der Virologie. Unter Anderem für die Zählung von Placques und Foci stehen spezielle Softwaremodule zur Verfügung. Zytopathische Effekte, Assays für neutralisierende Antikörper und Proteinbindungen gehören ohnehin zum Standard-Repertoire der Celigo-Software-Suite. Gerade in diesen Tagen entdecken viele Labore den enormen Gewinn an Effizienz und Reproduzierbarkeit in der Automatisierung dieser Assays.
Aktuelle Veröffentlichungen aus der Virologie mit dem Celigo
- An In Vitro Microneutralization Assay for SARS-CoV-2 Serology and Drug Screening
- Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
- CD46 facilitates entry and dissemination of human cytomegalovirus
- Antibodies Elicited by an NS1-Based Vaccine Protect Mice against Zika Virus
- IL-6 ameliorates acute lung injury in influenza virus infection
- A high-throughput inhibition assay to study MERS-CoV antibody interactions using image cytometry
- Single-dose intranasal vaccination elicits systemic and mucosal immunity against SARSCoV-2
- Susceptibility of widely diverse influenza a viruses to PB2 polymerase inhibitor pimodivir
- A comprehensive influenza reporter virus panel for high-throughput deep profiling of neutralizing antibodies
- Broad Spectrum Inhibitor of Influenza A and B Viruses Targeting the Viral Nucleoprotein
- A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research
- Integration of Fluorescence Detection and Image-Based Automated Counting Increases Speed, Sensitivity, and Robustness of Plaque Assays
- Inhibition of large T antigen ATPase activity as a potential strategy to develop anti-polyomavirus JC drugs
- Innate Immune Response to Influenza Virus at Single-Cell Resolution in Human Epithelial Cells Revealed Paracrine Induction of Interferon Lambda 1
- A Short Hairpin RNA Screen of Interferon-Stimulated Genes Identifies a Novel Negative Regulator of the Cellular Antiviral Response
- An Influenza Virus Hemagglutinin-Based Vaccine Platform Enables the Generation of Epitope Specific Human Cytomegalovirus Antibodies
- A respiratory syncytial virus (RSV) F protein nanoparticle vaccine focuses antibody responses to a conserved neutralization domain
- Purified Inactivated Zika Vaccine Candidates Afford Protection against Lethal Challenge in Mice
- A Next Generation Bivalent Human Ad5 COVID-19 Vaccine Delivering Both Spike and Nucleocapsid Antigens Elicits Th1 Dominant CD4+, CD8+ T-cell and Neutralizing Antibody Responses
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