Multiplexed imaging and spatial analysis used to be complex, requiring specialized expertise and bulky instrumentation.
With the Orion platform, RareCyte delivers high-plex fluorescence imaging and biomarker analysis in a streamlined workflow for any research lab. Whether conducting multiplexed tissue imaging on slides or high-throughput analysis across cohorts, Orion enables rapid, high-quality spatial biology insights without the need for spectral unmixing.
Leveraging its proprietary multi-epitope detection technology, Orion combines speed, simplicity, and scalability—empowering researchers with unparalleled spatial resolution and flexibility for biomarker discovery.

RareCyte Orion
Tissue consists of heterogenous cell types, each with diverse functions and functional states, arranged spatially in a way that impacts patient health status.
Resolving this complexity has been challenged by:
- Fluorescence overlap and autofluorescence
- Low throughput due to long staining or acquisition times
Orion technology breaks these barriers, providing rapid, straightforward, highly multiplexed whole slide tissue analysis
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Specifications
Sample compatibility: IF, IHC, H&E
Scan speed: 75 mins per cm2 at 20x
Excitation Lasers: 402 nm - 808 nm
Emission: Tunable from 425 - 894 nm
Slide compatibility: 1” x 3” x 1 mm, 25 mm x 75 mm x 1 mm
Slide capacity: 2 slides
Slide loading: Manual
Load repeatability: +/- 5.0 μm
Focus: Image-based Autofocus
Objectives: 4X 0.2 NA, 20X 0.8 NA
Camera: sCMOS; 2048 x 2048 pixels, 6.5 μm pixel size, 95% QE. 1.0 electron read noise
Safety: Class I LASER Product
File format: 16-bit OME .TIFF